Sunday, February 15, 2015

More about reducing your risk of dying


Remember the research stating that the number of deaths reduced from walking 20 minutes a day could theoretically be doubled with an approach that also avoided a high body mass index (BMI) or a high waist circumference?

A Canadian study supports this where the researchers concluded that physical inactivity and a high waist circumference have a significant independent risk of premature mortality among women (Katzmarzyk PT, Craig CL, 2006).

The participants of this study were all women, but other research has shown that this also works for men.
What if you could implement an activity more effective than walking?

What about an activity were you only spent 3 minutes of actual exercise time, 3 times a week, and the research had shown that this decreased the fat percentage by 8 percent and decreased waist circumference by 3.5 percent in 6 weeks (Hazell TJ, et al. 2014).

The participants in this study were women, and they ran all-out sprints on a self-propelled treadmill for 30 seconds, then rested for 4 minutes. They repeated this 4-6 to times 3 times a week. You don't have to run on a treadmill, you can run outdoors, that's even easier.

Katzmarzyk PT1, Craig CL. Independent effects of waist circumference and physical activity on all-cause mortality in Canadian women. Appl Physiol Nutr Metab. 2006 Jun;31(3):271-6.
Hazell TJ1, Hamilton CD, Olver TD, Lemon PW. Running sprint interval training induces fat loss in women. Appl Physiol Nutr Metab. 2014 Aug;39(8):944-50. doi: 10.1139/apnm-2013-0503. Epub 2014 Mar 18.

Published with permission by Didrik Sopler, Ph.D., L.Ac : www.TissueRecovery.com Dr. Marsh has worked with and referrers patients to Dr. Sopler for co-management for years . . . He is quite simply San Diego's top functional medicine consultant.

Ingredient in spice you can use to improve cognition


In the referenced study the researchers investigated if curcumin, an ingredient of the spice turmeric, would have an effect on cognitive function(Cox KH, et Al. 2014).

The participants were healthy adults between the age of 60 and 85 years, and the research was double blinded.

A special formulation of curcumin was used since regular curcumin is very poorly absorbed.

It was found that one hour after taking this curcumin the participants significantly improved performance on sustained attention and working memory tasks compared with the placebo. Taking it every day for four weeks resulted in a significantly better working memory and mood. It also reduced total cholesterol and LDL cholesterol.

I have found that another special formulation of curcumin has reduced hs-CRP, an inflammatory marker. Curcumin is also known to be a good antioxidant.

Cox KH1, Pipingas A1, Scholey AB2. Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population. J Psychopharmacol. 2014 Oct 2. pii: 0269881114552744. [Epub ahead of print]

Published with permission by Didrik Sopler, Ph.D., L.Ac : www.TissueRecovery.com Dr. Marsh has worked with and referrers patients to Dr. Sopler for co-management for years . . . He is quite simply San Diego's top functional medicine consultant.

Higher intake of this important mineral shows reduced risk for metabolic syndrome


People with metabolic syndrome have a cluster of symptoms. They are usually insulin resistant, they usually have high blood pressure and also high cholesterol and triglycerides.

The reviewed research included a total of 24,473 individuals and 6,311 cases of metabolic syndrome(Dibaba DT et al. 2014). The participants with the highest dietary intake of Magnesium were compared with the ones with the lowest intake.

The results showed that for every 100 mg per day increment in magnesium intake the overall risk of having metabolic syndrome was lowered by 17 percent.

Magnesium is a very important mineral, but all minerals should be taken together with other minerals since they affect each other. For example, magnesium regulates intra and extra cellular calcium levels, and if you only take zinc, you will lose copper.

The most common form of magnesium is magnesium oxide which is very poorly absorbed and irritates the gastrointestinal tract.

Magnesium in the form of an amino acid chelate does not have that effect and is also much better absorbed and is a better choice.

Dibaba DT, Xun P, Fly AD, Yokota K, He K. Dietary magnesium intake and risk of metabolic syndrome: a meta-analysis. Diabet Med. 2014 Nov;31(11):1301-9. doi: 10.1111/dme.12537.

Published with permission by Didrik Sopler, Ph.D., L.Ac : www.TissueRecovery.com Dr. Marsh has worked with and referrers patients to Dr. Sopler for co-management for years . . . He is quite simply San Diego's top functional medicine consultant.

Protect your memory with something you enjoy eating


The reviewed research first mapped out the precise brain location for age-related dysfunction using functional MRI.

The researchers then had 50-69 year old participants either consume a high or a low cocoa flavanol diet for 3 months(Brickman AM,et al. 2014).

The results showed that a high flavanol diet was found to enhance dentate gurus function, that is the function related to memory dysfunction, when measured with functional MRI and cognitive testing.

To increase your cocoa flavanol intake you can either eat some dark chocolate with a high flavanol content or drink some cocoa. Dark chocolate and cocoa are bitter; for that reason sugar is added of course, so be sure to watch your sugar levels with chocolate. The more bitter you can handle the better.

Brickman AM, Khan UA, Provenzano FA, Yeung LK, Suzuki W, Schroeter H, Wall M, Sloan RP, Small SA.
Enhancing dentate gyrus function with dietary flavanols improves cognition in older adults. Nat Neurosci. 2014 Dec;17(12):1798-803. doi: 10.1038/nn.3850. Epub 2014 Oct 26.

Published with permission by Didrik Sopler, Ph.D., L.Ac : www.TissueRecovery.com Dr. Marsh has worked with and referrers patients to Dr. Sopler for co-management for years . . . He is quite simply San Diego's top functional medicine consultant.

See what pistachio nuts can do for you


If you want a quick healthy snack, then pistachio nuts would be a good choice.

The reviewed research had diabetic patients either assigned to a group receiving 25 g of pistachio nuts twice a day as a snack or a control meal without nuts(Parham M, et al. 2014).

After 12 weeks the participants had a washout period of 8 weeks before the groups were switched.

The results showed that eating pistachios decreased HbA1c (a long-term measure of glucose control) as well as fasting blood glucose. Eating the nuts also reduced systolic blood pressure, body mass index and CRP an inflammatory marker.

Nuts are a much better choice than so called nutrition bars if you want a snack.

Parham M1, Heidari S2, Khorramirad A2, Hozoori M3, Hosseinzadeh F1, Bakhtyari L4, Vafaeimanesh J1.Effects of pistachio nut supplementation on blood glucose in patients with type 2 diabetes: a randomized crossover trial. Rev Diabet Stud. 2014 Summer;11(2):190-6. doi: 10.1900/RDS.2014.11.190. Epub 2014 Aug 10.

Published with permission by Didrik Sopler, Ph.D., L.Ac : www.TissueRecovery.com Dr. Marsh has worked with and referrers patients to Dr. Sopler for co-management for years . . . He is quite simply San Diego's top functional medicine consultant.

Easy way to reduce your risk for Alzheimer's disease


The reviewed research followed 1,658 adults who were free from dementia, cardiovascular disease and stroke for an average of 5.6 years (Littlejohns TJ, et al. 2014).

Vitamin D levels (25-hydroxy vitamin D) were measured from blood samples.

It was found that vitamin D deficiency is associated with a substantially increased risk for both dementia and Alzheimer's disease.

For most people 2000 IU daily of vitamin D 3 is enough to maintain a good level of vitamin D. That should be easy to manage, and if you also get out in the sun a little bit without sunscreen, you should be even better off.

Littlejohns TJ, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PH, Fried L, Kestenbaum BR, Kuller LH, Langa KM, Lopez OL, Kos K, Soni M, Llewellyn DJ. Vitamin D and the risk of dementia and Alzheimer disease. Neurology. 2014 Sep 2;83(10):920-8. doi: 10.1212/WNL.0000000000000755. Epub 2014 Aug 6.

Published with permission by Didrik Sopler, Ph.D., L.Ac : www.TissueRecovery.com Dr. Marsh has worked with and referrers patients to Dr. Sopler for co-management for years . . . He is quite simply San Diego's top functional medicine consultant.

Tuesday, December 9, 2014

Elevated levels of common lab test associated with increased risk for Alzheimer's


There is no single test available at the time to specifically diagnose Alzheimer's disease or to only show the risk for it. New research, however, indicates that a common test like fasting glucose may tell us something about the risk (Burns CM, et al. 2014).

When regional cerebral metabolic rate for glucose in brain regions usually affected by Alzheimer disease was measured, a correlation with fasting glucose levels was found. Higher fasting glucose levels in cognitively normal, non diabetic adults were correlated with lower regional cerebral metabolic rate.

This means that higher fasting glucose levels may be associated with the pathophysiology of Alzheimer's disease and increase the risk for this disease.

What is the solution? A diet consisting of high nutrient, low glycemic index food, exercise and meditation for better handling of stress.

This type of lifestyle will also reduce the risk for all other chronic conditions as well.

Burns CM1, Chen K, Kaszniak AW, Lee W, Alexander GE, Bandy D, Fleisher AS, Caselli RJ, Reiman EM.Higher serum glucose levels are associated with cerebral hypometabolism in Alzheimer regions. Neurology. 2013 Apr 23;80(17):1557-64. doi: 10.1212/WNL.0b013e31828f17de. Epub 2013 Mar 27.

Published with permission by Didrik Sopler, Ph.D., L.Ac : www.TissueRecovery.com Dr. Marsh has worked with and referrers patients to Dr. Sopler for co-management for years . . . He is quite simply San Diego's top functional medicine consultant.